Proinflammatory Cytokine Single Nucleotide Polymorphisms in Nasal Polyposis
نویسندگان
چکیده
منابع مشابه
Proinflammatory cytokine single nucleotide polymorphisms in nasal polyposis.
OBJECTIVE To investigate the association between nasal polyposis (NP) and single nucleotide polymorphisms of the proinflammatory cytokines IL (interleukin) 1alpha (the IL1A gene), IL-1beta (the IL1B gene), and tumor necrosis factor alpha (the TNFA gene). DESIGN Prospective case-control trial. SETTING Tertiary referral center. PATIENTS Eighty-two patients with NP and 106 healthy volunteers...
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The aim of this prospective study was to evaluate whether cytokine levels in nasal secretions may be clinical parameters of severity of nasal polyposis. Forty nasal polyp patients (20 asthmatic and 20 nonasthmatic) requiring surgical treatment were included. Nasal secretion samples were collected from nasal cavities of all 40 subjects. The levels of T-helper type 1 (Th1) proinflammatory cytokin...
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Cytokines are important immunomodulatory molecules involved in immune responses against microorganisms; they also have an important role in the setting of immune system disorders. Cytokine single nucleotide polymorphisms have been extensively studied in different, normal populations as well as in association with disease. Cytokine gene polymorphisms are potentially important as genetic predicto...
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ژورنال
عنوان ژورنال: Archives of Otolaryngology–Head & Neck Surgery
سال: 2007
ISSN: 0886-4470
DOI: 10.1001/archotol.133.7.705